Patent · US Active

Composition for transdermal delivery of cationic active agents

US10881607B2 · kind B2 · utility

5Cited by

8References

21Claims

0Family size

Assignee

LTS Lohmann Therapie-Systeme AG · DE

Inventors

Christoph Schmitz · Euskirchen, DE
Mohammad Sameti · Bonn, DE
Andreas Koch · Heiligenhaus, DE
Michael Horstmann · Neuwied, DE

Key dates

Filing date	Dec 16, 2019
Grant date	Jan 5, 2021
Priority date	—
Expiry date	Dec 16, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a composition for transdermal delivery, particularly iontophoretic transdermal delivery, of at least one cationic active agent or a salt thereof. The composition includes at least one cationic active agent or a salt thereof, at least one polyamine or/and polyamine salt, water or an aqueous solvent mixture, and optionally one or more additives. The invention further relates to the use of such composition as a component of a transdermal patch or of an iontophoretic transdermal patch, as well as to the use of such composition in a method for transdermally and/or iontophoretically administering cationic active agents. The invention further includes methods for determining the in vitro skin permeation properties of an active-agent-containing iontophoretic composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.