Cholestyramine granules, oral cholestyramine formulations and use thereof
US10881685B2 · kind B2 · utility
2Cited by
62References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 7, 2018 |
| Grant date | Jan 5, 2021 |
| Priority date | — |
| Expiry date | Sep 7, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to small granules comprising cholestyramine. The granules have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such granules. The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine granules that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.