Patent · US Active

Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases

US10882855B2 · kind B2 · utility

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13Claims
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Key dates

Filing dateMay 10, 2019
Grant dateJan 5, 2021
Priority date
Expiry dateMay 10, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.