Taggable fluorescent probe for calcium ion detection
US10884004B2 · kind B2 · utility
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Key dates
| Filing date | Jan 13, 2017 |
| Grant date | Jan 5, 2021 |
| Priority date | — |
| Expiry date | Feb 16, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC09K2211/1018
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A fluorescent probe for calcium ion detection that has an excellent photofading resistance and quick Ca2+ detection kinetics and can be localized at an arbitrary site in a cell is provided. The fluorescent probe contains a compound represented by the following general formula (I) or a salt thereof:A method for detecting intracellular calcium ions including (a) introducing the compound above or a salt thereof into a cell and (b) measuring the fluorescence emitted by the compound or a salt thereof in the cell is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.