Methods for variant detection
US10886006B2 · kind B2 · utility
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41Claims
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Key dates
| Filing date | Apr 13, 2017 |
| Grant date | Jan 5, 2021 |
| Priority date | — |
| Expiry date | Oct 30, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention can be used to provide a more efficient and less error-prone method of detecting variants in DNA, such as SNPs and indels. The invention also provides a method for performing inexpensive multiplex assays. The invention also provides methods for detection of DNA sequences altered after cleavage by a targetable endonuclease, such as the CRISPR Cas9 protein from the bacterium Streptococcus pyogenes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.