Biemamides and related scaffolds as inhibitors of transforming growth factor-beta signaling
US10889551B2 · kind B2 · utility
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Key dates
| Filing date | Aug 26, 2019 |
| Grant date | Jan 12, 2021 |
| Priority date | — |
| Expiry date | Aug 26, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present technology provides an isolated compound of Formula I, compositions including such compounds, methods of inhibiting TGF-β signaling and/or TGF-β induced epithelial mesenchymal transitions (EMT), and treating certain cancers involving TGF-β signaling and/or EMT.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.