Anthelmintic quinoline-3-carboxamide derivatives

US10889573B2 · kind B2 · utility

Assignee

• Bayer Animal Health GmbH · DE

Inventors

• Walter Hubsch · Wuppertal, DE
• Johannes Köbberling · Neuss, DE
• Adeline Köhler · Langenfeld, DE
• Hans-Georg Schwarz · Dorsten, DE
• Daniel KULKE · Leverkusen, DE
• Claudia WELZ · Goldkronach, DE
• Thomas ILG · Monheim, DE
• Kirsten BÖRNGEN · Neunburg vorm Wald, DE
• Wei Zhuang · Monheim, DE
• Nils Griebenow · Milford, US
• Claudia Böhm · Hannover, DE
• Niels Lindner · Wuppertal, DE
• Maike Hink · Markgröningen, DE
• Ulrich Görgens · Ratingen, DE

Key dates

• Filing date: Nov 6, 2017
• Grant date: Jan 12, 2021
• Expiry date: Nov 6, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention covers new quinoline compounds of general formula (I) in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.