Patent · US Active

Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof

US10889580B2 · kind B2 · utility

2Cited by

1References

20Claims

0Family size

Assignee

VTV THERAPEUTICS LLC · US

Inventors

Adnan M. M. Mjalli · Oak Ridge, US
Dharma Rao Polisetti · High Point, US
Jareer Nabeel Kassis · Colfax, US
Matthew J. Kostura · Hillsborough, US
Mustafa Guzel · Jamestown, US
Otis Clinton Attucks · Winston-Salem, US
Robert Carl Andrews · Jamestown, US
Samuel Victory · Oak Ridge, US
Suparna Gupta · Greensboro, US

Key dates

Filing date	Jan 10, 2020
Grant date	Jan 12, 2021
Priority date	—
Expiry date	Jan 10, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D513/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Substituted fused imidazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted fused imidazole derivative, and methods of use in treating non-alcoholic steatohepatitis are provided. The substituted fused imidazole derivatives may control the activity or the amount or both the activity and the amount of heme-oxygenase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.