Production of N-glycoproteins for enzyme assisted glycomodification
US10889845B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jun 15, 2016 |
| Grant date | Jan 12, 2021 |
| Priority date | — |
| Expiry date | Jun 15, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a cell comprising a gene encoding a polypeptide of interest, wherein the polypeptide of interest is expressed comprising one or more posttranslational modification patterns. These modifications are useful for example in improvement of pharmacokinetic properties, i.e. by attaching PEG chains to proteins. The present invention also relates to methods for producing the antibodies and compositions comprising the antibodies, and their uses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.