Splice variants associated with neomorphic SF3B1 mutants
US10889866B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Aug 30, 2016 |
| Grant date | Jan 12, 2021 |
| Priority date | — |
| Expiry date | Jan 23, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Splice variants associated with neomorphic SF3B1 mutations are described herein. This application also relates to methods of detecting the described splice variants, and uses for diagnosing cancer, evaluating modulators of SF3B1, and methods of treating cancer associated with mutations in SF3B1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.