Pharmaceutical formulation of palbociclib and a preparation method thereof
US10894049B2 · kind B2 · utility
1Cited by
14References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 28, 2019 |
| Grant date | Jan 19, 2021 |
| Priority date | — |
| Expiry date | Aug 28, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.