Patent · US Active

TAL-Tet1 fusion proteins and methods of use thereof

US10894950B2 · kind B2 · utility

2Cited by

19References

14Claims

0Family size

Assignee

The General Hospital Corporation · US

Inventors

J. Keith Joung · Winchester, US
Morgan Maeder · Brookline, US
James Angstman · Boston, US

Key dates

Filing date	Feb 12, 2018
Grant date	Jan 19, 2021
Priority date	—
Expiry date	Dec 28, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/81
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array or zinc finger, and a catalytic domain comprising a sequence that catalyzes hydroxylation of methylated cytosines in DNA, and methods of use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.