Bipolar electrode for the impedimetric examination and manipulation of living cells in vitro

US10895546B2 · kind B2 · utility

Assignees

• Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE
• UNIVERSITAET REGENSBURG · DE

Inventors

• Christian Goetz · Seligenstadt, DE
• Joachim Wegener

Key dates

• Filing date: Dec 12, 2017
• Grant date: Jan 19, 2021
• Expiry date: Jan 11, 2038

Classification

• Technology area (CPC H): Electricity
• CPC primary: H01B1/128
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present disclosure relates to a measuring device with a bipolar electrode array for the impedimetric analysis of adherent cells according to the ECIS principle (electric cells substrate impedance sensing). The measuring device comprises an electrode array which is adapted for being wetted with an electrolyte solution and adherently growing cells in order to perform impedimetric cell analyzes, characterized in that the electrode array comprises a bipolar electrode on a substrate, where the bipolar electrode is formed as a conductive path on the transparent substrate and has an inherent resistance between two connection points of the conductive path that is a multiple of the AC impedance of the electrolyte solution at 1 MHz, measured at the two connection points.