Patent · US Active

Processes and intermediates for making a JAK inhibitor

US10899736B2 · kind B2 · utility

6Cited by

101References

43Claims

0Family size

Assignee

Incyte Corporation · US

Inventors

Dengjin Wang · Levittown, US
Pingli Liu · Wilmington, US
Yongzhong Wu · Chadds Ford, US
Jiacheng Zhou · Shanghai, CN

Key dates

Filing date	Jan 29, 2019
Grant date	Jan 26, 2021
Priority date	—
Expiry date	Jan 29, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.