Imidazo isoindole derivative, preparation method therefor and medical use thereof
US10899764B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 12, 2016 |
| Grant date | Jan 26, 2021 |
| Priority date | — |
| Expiry date | Apr 12, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an imidazo isoindole derivative, a preparation method therefor and a medical use thereof. In particular, the present invention relates to the imidazo isoindole derivative as shown in the formula (I), a preparation method and pharmaceutical composition containing the derivative, and a use thereof for treating diseases with a pathological characteristic of the IDO-mediated tryptophan metabolic pathways. The diseases comprise cancers, Alzheimer's disease, autoimmune diseases, depression, anxiety disorders, cataracts, psychological disorders and AIDS, wherein the substituents in the formula (I) are the same as those defined in the specification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.