Production method for insoluble recombinant protein aggregate
US10899792B2 · kind B2 · utility
1Cited by
1References
17Claims
0Family size
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Key dates
| Filing date | Aug 10, 2017 |
| Grant date | Jan 26, 2021 |
| Priority date | — |
| Expiry date | Aug 10, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An object of the present invention is to provide a method for efficiently separating insoluble bodies of a recombinant protein from a recombinant cell expressing a target recombinant protein as insoluble bodies in the cell. The present invention provides a method for producing a recombinant protein aggregate by separating insoluble bodies of a recombinant protein from a recombinant cell expressing the recombinant protein as insoluble bodies in the cell, including disrupting the recombinant cell, aggregating the insoluble bodies of the recombinant protein, and separating the resulting aggregate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.