Chemical modulators of signaling pathways and therapeutic use
US10905665B2 · kind B2 · utility
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Key dates
| Filing date | Jun 24, 2016 |
| Grant date | Feb 2, 2021 |
| Priority date | — |
| Expiry date | Sep 12, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are methods of treating a disease associated with dysregulation of the Wnt/Frizzled signaling pathway. The methods include identifying subjects in need of therapy, administering inhibitors of the Wnt/Frizzled signaling pathway, pharmaceutical compositions including the inhibitors, and methods of using the compounds and compositions for treating cancer, bacterial and viral infection, lupus, type II diabetes, nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.