Synthetic peptides, prodrugs, pharmaceutical compositions and uses
US10905738B2 · kind B2 · utility
Assignee
Inventors
- Caio Victor Machado França do Nascimento
- Diego Allonso Rodrigues dos Santos da Silva
- Perla Villani Borges da Silva
- Maria Elena De Lima Perez Garcia
- Carolina Nunes da Silva
- Adriano Monteiro de Castro Pimenta
- Marcella Nunes de Melo Braga
- Paulo Gustavo Sampaio Lacativa
- Iron Francisco de Paula Junior
- Gerhard Max Gross
Key dates
| Filing date | Jul 3, 2019 |
| Grant date | Feb 2, 2021 |
| Priority date | — |
| Expiry date | Jul 3, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Synthetic peptides that are modulators of smooth muscle tone and compositions thereof, including pharmaceutical compositions containing a peptide, make it possible to treat indications in those in need of modulation of the smooth muscle tone, including, for example, benign prostate hyperplasia (BPH), Raynaud's syndrome, Pulmonary Arterial hypertension (PAH), systemic arterial hypertension (SAH) and hyper-reactivity of airways associated with asthma, COPD, pulmonary fibrosis, silicosis, allergic bronchopulmonary aspergillosis, hereditary angioedema, and neonatal hypoxemic respiratory failure. Although makeable in other ways, the synthetic peptides are makeable by recombinant methods or synthetic pathways.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.