Compounds, systems, and methods for monitoring and treating a surface of a subject
US10905780B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 3, 2018 |
| Grant date | Feb 2, 2021 |
| Priority date | — |
| Expiry date | Aug 3, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2013/0097
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds, systems, and methods are provided for the design and assembly of a non-invasive, analyte sensing dressing. The dressing can be therapeutic. The dressing includes a sensor and a matrix. The sensor is capable of detecting analytes such as molecular oxygen, carbon dioxide, nitric oxides, dissolved analytes in plasma, and hydrogen ions. The matrix is at least partially permeable to the analyte. The device emits a detectable signal when the sensor is excited in the presence of the analyte. In one version of the dressing, the sensor includes a meso-unsubstituted metallated porphyrin that is sensitive towards oxygen. The metallated porphyrin can be excited when illuminated at a first wavelength, followed by emission of phosphorescence at a second wavelength whose intensity can be used as an indicator for oxygen concentration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.