Process-scale synthesis of urolithin A

US10906883B2 · kind B2 · utility

Assignee

• Amazentis SA · CH

Inventors

• Wolfgang Skranc · Wien, AT
• George Petros Yiannikouros · Florence, US
• Alexander Trofimov · Florence, US
• Zhixing Shan · Albany, US
• Christopher Goss · Florence, US

Key dates

• Filing date: Feb 27, 2019
• Grant date: Feb 2, 2021
• Expiry date: Feb 27, 2039

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01J27/055
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are methods for preparing a salt of urolithin A and, in turn, urolithin A. The methods are advantageous for the large-scale preparation of urolithin A or a pharmaceutically acceptable salt thereof.