Patent · US Active

Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria

US10907180B2 · kind B2 · utility

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1References

20Claims

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Assignee

Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen · DE

Inventors

Lars Blank · Dortmund, DE
Till Tiso · Cologne, DE
Andrea Germer · Aachen, DE

Key dates

Filing date	Jul 6, 2016
Grant date	Feb 2, 2021
Priority date	—
Expiry date	Jul 6, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y204/01
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a host cell comprising an rhlA gene or an ortholog thereof that is capable of producing hydroxyalkanoyloxy alkanoic acid (HAA) and achieving an HAA concentration of more than 1 g L−1 when cultured. The invention further relates to methods of producing such a host cell and to the use of said host cell for producing HAA. The present invention also relates to methods of producing HAA using said host cell, HAA compositions produced by these methods, as well as methods of producing fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions comprising producing HAA using said host cell, and fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions produced by said methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.