Microarray slides that enhance fluorescent signals via plasmonic interaction
US10908090B2 · kind B2 · utility
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2References
26Claims
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Assignee
Inventor
Key dates
| Filing date | Mar 7, 2016 |
| Grant date | Feb 2, 2021 |
| Priority date | — |
| Expiry date | Nov 5, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/06113
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention describes generating and use of a multi-layer plasmonic slide, wherein the plasmonic slide comprises at least 6 layers of metallic nanoparticles that can enhance the detection of fluorescent signals and wherein the plasmonic slide can be printed as a microarray of any size. The microarray containing the plasmonic slide can further be printed with a protein, a glycan, or an antibody. The multi-layer plasmonic slide is capable of detecting proteins, polynucleotides, and/or glycans at orders of magnitude lower concentration than non-plasmonic substrates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.