Methods for preparing botanical extracts

US10912812B2 · kind B2 · utility

Assignee

• Signum Biosciences, Inc. · US

Inventors

• Kristen Huber · Monmouth Junction, US
• Michael Voronkov · Cranbury, US
• Jose Fernandez · Monmouth Junction, US
• Karl Rouzard · Monmouth Junction, US
• Eduardo Perez · Somerville, US
• Maxwell Stock · Boulder, US
• Jeffry B. Stock · Princeton, US

Key dates

• Filing date: Jul 17, 2019
• Grant date: Feb 9, 2021
• Expiry date: Jul 17, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Method of preparing a botanical extract that includes contacting a raw botanical with a solvent having a dielectric constant ranging from about 2.3 to about 25 and allowing the mixture to reside for a sufficient time to obtain a crude extract; filtering out remaining raw botanical and evaporating the solvent from the crude extract under reduced pressure to obtain a dried crude extract; washing the dried crude extract with a polar solvent having a dielectric constant of no less than 30, heating the resulting mixture, and allowing to cool to ambient; collecting a filtrate from the above cooled mixture; washing the collected filtrate with a non-polar solvent having a dielectric constant of no more than 2.0; and filtering and drying the mixture to obtain the botanical extract.