Efficient process for the preparation of sitagliptin through a very effective preparation of the intermediate 2,4,5-trifluorophenylacetic acid
US10913747B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | May 15, 2018 |
| Grant date | Feb 9, 2021 |
| Priority date | — |
| Expiry date | May 15, 2038 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J27/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Object of the present invention is an efficient process for the preparation of the active pharmaceutical ingredient Sitagliptine and the 2,4,5-trifluorophenylacetic acid (TFAA) and salt thereof, which is a key intermediate for the synthesis of Sitagliptine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.