Microfluidic platform device and method for identifying neutralizing and/or enhancing antibodies through direct functional assays
US10914727B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 19, 2016 |
| Grant date | Feb 9, 2021 |
| Priority date | — |
| Expiry date | Feb 13, 2037 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2200/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The microfluidic platform device of the claimed invention makes use of a high throughput lab-on-a-chip format to determine the functional profile of antibodies elicited by infection or vaccination against infection for any pathogen. It can be used to evaluate vaccines, evaluate whether vaccinated individuals show indices of protection, determine whether individuals display resistance or susceptibility to infection, discover new vaccine antigens, discover and test therapeutic interventions, or evaluate mechanisms of disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.