Controlled-release CNS modulating compositions and methods for the treatment of otic disorders

US10918594B2 · kind B2 · utility

Assignees

• OTONOMY, INC. · US
• The Regents of the University of California · US

Inventors

• Jay Lichter · Rancho Santa Fe, US
• Andrew M. Trammel · Olathe, US
• Fabrice Piu · San Diego, US
• Qiang Ye · San Diego, US
• Michael Christopher Scaife · Pittsburgh, US
• Benedikt Vollrath · San Diego, US
• Sergio G. Duron · San Diego, US
• Luis A. Dellamary · San Marcos, US
• Carl Lebel · Malibu, US
• Jeffrey P. Harris · Village of La Jolla, US

Key dates

• Filing date: Jun 20, 2019
• Grant date: Feb 16, 2021
• Expiry date: Jun 20, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).