Patent · US Active

N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors

US10918642B2 · kind B2 · utility

2Cited by
2References
1Claims
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Assignee

Inventors

Key dates

Filing dateDec 19, 2019
Grant dateFeb 16, 2021
Priority date
Expiry dateDec 19, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to N-(substituted-phenyl)-sulfonamide compounds, which are extremely useful as inhibitors of protein kinases (e.g. PERK kinase) and accordingly can be used for the treatment of cell proliferative disorders, such as cancer, or diseases associated with activated unfolded protein response pathways, such as Alzheimer's disease. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.