Patent · US Active

Prion protein antibodies for the treatment of Alzheimer's disease

US10919971B2 · kind B2 · utility

2Cited by
1References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 30, 2019
Grant dateFeb 16, 2021
Priority date
Expiry dateApr 30, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of impaired synaptic plasticity. The invention also relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of toxicity of Aβ oligomers. The invention also relates to a ligand capable of binding PrP at a site within amino acid residues 131 to 153 of PrP, for use in treatment or prevention of Alzheimer's Disease. The invention also relates to methods of medical treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.