Patent · US Active

Bispecific tetravalent antibodies and methods of making and using thereof

US10919977B2 · kind B2 · utility

2Cited by

0References

29Claims

0Family size

Assignees

SystImmune, Inc. · US
Sichuan Baili Pharmaceutical Co. Ltd. · CN

Inventors

Zeren Gao · Redmond, US
Phil Tan · Edmonds, US
Brian R. Kovacevich · Snohomish, US
Blair R. Renshaw · Renton, US
Jeffrey B. Adamo · Bellevue, US
Nga Sze Amanda Mak · Bellevue, US
Shi ZHUO · Sichuan, CN
Lan Bo Chen · Boston, US
Yi Zhu · Chengdu, CN

Key dates

Filing date	Dec 19, 2015
Grant date	Feb 16, 2021
Priority date	—
Expiry date	Dec 19, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/94
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.