Patent · US Active

Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

US10920227B2 · kind B2 · utility

8Cited by

235References

22Claims

0Family size

Assignee

VOYAGER THERAPEUTICS, INC. · US

Inventors

Dinah Wen-Yee Sah · Boston, US
Jinzhao Hou · Cambridge, US
Mathieu E. Nonnenmacher · Boston, US
Pengcheng Zhou · Lexington, US
Markus Hossbach · Kulmbach, DE
Jochen Deckert · Bayreuth, DE

Key dates

Filing date	Jan 28, 2020
Grant date	Feb 16, 2021
Priority date	—
Expiry date	Jan 28, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14143
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to small interfering RNA (siRNA) molecules against the SOD1 gene, adeno-associated viral (AAV) vectors encoding siRNA molecules and methods for treating amyotrophic lateral sclerosis (ALS) using the siRNA molecules and AAV vectors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.