Method of making an integrated circuit for a single-molecule nucleic-acid assay platform

US10921314B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Kenneth L. Shepard · Johnstown, US
• Steven Warren · New York, US
• Scott Trocchia · Edgewater, US
• Yoonhee Lee · Suwon-si, KR
• Erik B. YOUNG · Tappan, US

Key dates

• Filing date: May 31, 2019
• Grant date: Feb 16, 2021
• Expiry date: May 31, 2039

Classification

• Technology area (CPC H): Electricity
• CPC primary: H10K10/484
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods of making an integrated circuit for a single-molecule nucleic-acid assay platform. In one example, the method includes adhering a carbon nanotube to a surface of a transfer film, the transfer film comprising gold or a polymer; placing the surface of the transfer film on a CMOS integrated circuit; releasing the carbon nanotube from the transfer film; and forming a pair of post-processed electrodes proximate opposing ends of the carbon nanotube, the post-processed electrodes electrically connecting the carbon nanotube to the CMOS integrated circuit. The method can also include exposing the carbon nanotube to a diazonium salt solution to form a point defect on a portion of the carbon nanotube.