Patent · US Active

Phase-contrast microscopy method, optical unit, and phase-contrast microscope

US10921572B2 · kind B2 · utility

1Cited by

2References

13Claims

0Family size

Assignee

Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE

Inventors

Friedrich Schenk · Aachen, DE
Benedict Diederich · Cologne, DE

Key dates

Filing date	Jan 11, 2018
Grant date	Feb 16, 2021
Priority date	—
Expiry date	Jan 11, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG02B21/365
WIPO fieldOptics
WIPO sectorInstruments

Abstract

A method for phase-contrast microscopy on a specimen, and the microscope and optical unit for carrying out the method, is provided. The specimen is arranged in a vessel having an object liquid, in which a component of an illumination beam, which serves as direct radiation and has not been diffracted by the sample, is applied to a phase-shifting element, is characterized in that the illumination beam is deflected before it enters the object liquid by way of an optical deflection element which is changeable in terms of position and/or shape so as to compensate for a change in the main radiation direction of the illumination beam that occurs due to optical refraction at the object liquid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.