Patent · US Active

Method for synthesizing 2-benzylidene tetrahydrothiophene derivative

US10927093B1 · kind B1 · utility

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Key dates

Filing dateFeb 26, 2018
Grant dateFeb 23, 2021
Priority date
Expiry dateFeb 26, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to a method for synthesizing a 2-benzylidene tetrahydrothiophene derivative, which comprises the step of reacting a (cyclopropylethynyl) aromatic cyclic compound of Formula (I) with a sulfur source in an organic solvent as a reaction medium in air atmosphere at 100-200° C. to obtain a 2-benzylidene tetrahydrothiophene derivative of Formula (III). The reaction route is as follows:

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