Wet adhesive peptide materials and their use

US10927148B2 · kind B2 · utility

Assignee

• The Government of the United States of America, as represented by the Secretary of the Navy · US

Inventors

• Christopher So · Henderson, US
• Kathryn J. Wahl · Alexandria, US

Key dates

• Filing date: Nov 6, 2018
• Grant date: Feb 23, 2021
• Expiry date: Nov 6, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09J2489/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Peptides that form adhesive bonds, even in aqueous and/or saline environments, are disclosed. When aggregated, the peptides may be used in methods for producing hydrogels and/or adhesive materials. Synthetic peptide analogs are provided that are designed based on protein sequences found in barnacle adhesive, and may optionally be augmented with chemistry from other organisms that secrete proteins that adhere to substrates. The peptides may be used, for example, in biomedical and aqueous applications. Methods of using the aggregated peptides as adhesives are also provided.