Cationic siRNAs, synthesis and use for RNA interference
US10927371B2 · kind B2 · utility
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23Claims
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Key dates
| Filing date | Jan 30, 2009 |
| Grant date | Feb 23, 2021 |
| Priority date | — |
| Expiry date | Mar 26, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to cationic siRNAs, characterized in that they are double-stranded RNA fragments, grafted to the ends of which are oligocations, the number of cationic charges grafted being comparable to or greater than that of the anionic charges carried by the internucleoside phosphates of the RNA strands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.