Oligonucleotides comprising modified nucleosides
US10927380B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Jun 30, 2017 |
| Grant date | Feb 23, 2021 |
| Priority date | — |
| Expiry date | Jun 30, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/31
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Polynucleotides, such as aptamers, comprising at least first one 5-position modified pyrimidine and at least one second 5-position modified pyrimidine are provided, wherein the first and second 5-position modified pyrimidines are different. Methods of selecting and using such polynucleotides, such as aptamers, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.