Rapid multiplexed infrared 3D nano-tomography

US10928311B2 · kind B2 · utility

Assignee

• The Government of the United States of America, as represented by the Secretary of the Navy · US

Inventors

• Robert Furstenberg · Burke, US
• Tyler Huffman · Alexandria, US
• Chris Kendziora · Burke, US
• R. Andrew McGill · Lorton, US

Key dates

• Filing date: Apr 12, 2019
• Grant date: Feb 23, 2021
• Expiry date: Apr 29, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/12
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method and system for rapid, label free nanoscale chemical imaging and tomography (3D) with multiplexing for speed, and engineered coherent illumination and detection to achieve 3-D resolution at twice the Abbe limit. A sample undergoes photo-thermal heating using a modulated infrared light source and the resulting probe beam modulation is measured with one or more visible laser probes. Varying the infrared wavelength results in a spectrum which characterizes the chemical composition of the sample. Optionally, inelastically scattered light generated as a result of the probe beam interacting with the sample is collected simultaneously to yield additional chemical information.