Patent · US Active

Luciferase-based thermal shift assays

US10928400B2 · kind B2 · utility

0Cited by

5References

9Claims

0Family size

Assignee

Promega Corporation · US

Inventors

Melanie Dart · Madison, US
Lance P. Encell · Fitchburg, US
Thomas Kirkland · Atascadero, US
Thomas Machleidt · Madison, US
Matthew Robers · Madison, US
Brock Binkowski · Sauk City, US
Keith V. Wood · Verona, US
Ce Shi · San Luis Obispo, US

Key dates

Filing date	Feb 11, 2020
Grant date	Feb 23, 2021
Priority date	—
Expiry date	Feb 11, 2040

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/10
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Provided herein are systems and methods for characterizing target/ligand engagement. In particular, luciferase-labeled polypeptide targets are used to detect or quantify target/ligand engagement (e.g., within a cell or cell lysate).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.