Device for the analysis of nucleic acid molecules
US10933416B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 6, 2016 |
| Grant date | Mar 2, 2021 |
| Priority date | — |
| Expiry date | May 6, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/07
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention proposes a device for analyzing nucleic acid molecules (M), comprising: —a bead (20), on which one molecule can be anchored at one end, —a surface (520), on which the molecule can be anchored at the other end, —an actuator (30), adapted to cause the bead to move relative to said surface in one direction, —a sensor (50), adapted to measure a distance between the bead and the surface, the device further comprising a well (11), having an axis (X-X) extending along the direction of motion of the bead and a bottom (110) formed by said surface, said well being filled with electrically conductive solution (40), and receiving the bead, the sensor being adapted to measure an impedance of the well, depending on a distance between the bead and the surface, to determine, the distance between the bead and the surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.