Patent · US Active

Compounds and compositions for inhibiting the activity of SHP2

US10934285B2 · kind B2 · utility

4Cited by
5References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 12, 2017
Grant dateMar 2, 2021
Priority date
Expiry dateJun 12, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula I: in which Y1, Y2, R1, R2 and R3 are defined in the Summary of the Invention; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.