Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions

US10939825B2 · kind B2 · utility

Assignees

• The General Hospital Corporation · US
• TRUSTEES OF BOSTON UNIVERSITY · US

Inventors

• Guillermo J. Tearney · Cambridge, US
• Brett Eugene Bouma · Quincy, US
• Hongki Yoo · Melrose, US
• Milen Shishkov · Acton, US
• Joseph A. Gardecki · Acton, US
• Roman Shubochkin · Arlington, US
• Theodore F. Morse · Providence, US
• Farouc Jaffer · Brookline, US

Key dates

• Filing date: Nov 22, 2016
• Grant date: Mar 9, 2021
• Expiry date: Nov 22, 2036

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/0866
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.