Anti-GCC antibody molecules and related compositions and methods
US10941211B2 · kind B2 · utility
0Cited by
40References
12Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 6, 2018 |
| Grant date | Mar 9, 2021 |
| Priority date | — |
| Expiry date | Jan 10, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/77
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The antibodies bind an extracellular domain of GCC and can be internalized. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.