Selecting and stabilizing dsRNA constructs
US10941398B2 · kind B2 · utility
0Cited by
8References
39Claims
0Family size
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Key dates
| Filing date | Nov 28, 2011 |
| Grant date | Mar 9, 2021 |
| Priority date | — |
| Expiry date | Jul 7, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A40/146
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.