Sequencing methods and compositions for prenatal diagnoses
US10941442B2 · kind B2 · utility
3Cited by
18References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 22, 2017 |
| Grant date | Mar 9, 2021 |
| Priority date | — |
| Expiry date | Nov 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/112
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA while expediting the process of analysis of samples for prenatal diagnoses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.