Method of screening for colorectal cancer
US10941449B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 17, 2013 |
| Grant date | Mar 9, 2021 |
| Priority date | — |
| Expiry date | Oct 7, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/50
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates generally to a method of determining one or more probabilities of respective classifications of a neoplasm into one or more neoplastic categories. More particularly, the present invention relates to a method of determining the probability of classification of a large intestine neoplasm into one or more categories selected from adenoma, stage I, stage II, stage III or stage IV by screening for changes to the methylation levels of a panel of gene markers, including BCAT1, IKZF1, IRF4, GRASP and/or CAHM. The method of the present invention is useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.