High throughput detection of pathogen RNA in clinical specimens
US10941453B1 · kind B1 · utility
2Cited by
20References
24Claims
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Key dates
| Filing date | May 20, 2020 |
| Grant date | Mar 9, 2021 |
| Priority date | — |
| Expiry date | May 20, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6874
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Laboratory-based high throughput methods and compositions (e.g., kits) for the detection of pathogen mRNA, including in particular, for the detection of SARS-CoV-2 RNA from up to 85,000 samples in one Illumina NovaSeq sequencing run. These methods may include barcoding cDNA, indexing pools of libraries and intensive use of automatic liquid handling, providing a ready-to-sequence library mix. These methods and compositions may allow a very inexpensive per sample cost and an assay that may be performed in about one day or less.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.