Use of biomarkers in the assessment of the early transition from arterial hypertension to heart failure

US10942175B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Ursula-Henrike Wienhues-Thelen · Krailling, DE
• Dirk Block · Bichl, DE
• Hendrik Huedig · Penzberg, DE
• Sabine Vogel-Ziebolz · Munich, DE
• Christine Boehm · Kreuzlingen, CH
• Georg Hess · Mainz, DE
• Andrea Horsch · Luzern, CH
• Dietmar Zdunek · Tutzing, DE

Key dates

• Filing date: Nov 21, 2014
• Grant date: Mar 9, 2021
• Expiry date: Nov 21, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods and systems for diagnosing functional and/or structural abnormalities of the heart preceding heart failure, and for predicting the risk of developing heart failure, in a subject comprising measuring a cardiac troponin in a sample and comparing the measurement to a reference value. Other markers, including GDF15 and IGFBP7 are also measured in some embodiments.