Combinations comprising a pyrrolidine-2,5-dione IDO1 inhibitor and an anti-body
US10945994B2 · kind B2 · utility
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Key dates
| Filing date | May 12, 2016 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | Oct 27, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2300/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Combinations of an IDO1 inhibitor (e.g., a 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione compound), with an anti-PD1 antibody or anti-PD-L1 antibody, and an anti-4-1BB antibody, as selected anti-cancer or anti-viral agents are provided. Also provided are use of these combinations for the treatment and/or prevention of cancer and endometriosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.