Method for sterilising a platelet lysate
US10946046B2 · kind B2 · utility
1Cited by
1References
7Claims
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Key dates
| Filing date | May 27, 2016 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | May 27, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2529/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for sterilising a platelet lysate in the liquid state comprising at least the endogenous growth factors TGF-beta 1, EGF, PDGF-AB, IGF-1, VEGF and bFGF. The method comprising freezing the liquid platelet lysate in order to obtain a frozen platelet lysate, and irradiating the frozen platelet lysate with ionising radiation in order to obtain a sterilised platelet lysate, the irradiation being adapted so as to preserve at least 80% of the concentration of at least one of the endogenous growth factors chosen from the group consisting of TGF-beta 1, EGF, PDGF-AB, IGF-1 and VEGF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.