Crystal form of dezocine and preparation method therefor
US10947185B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 22, 2018 |
| Grant date | Mar 16, 2021 |
| Priority date | — |
| Expiry date | May 22, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a crystal form of dezocine. The X-ray powder diffraction (XRD) pattern thereof is determined using Cu/K-α1 and has diffraction peaks at the 2θ value of 9.1±0.2 and 12.2±0.2, with the height % of these diffraction peaks greater than 20. Also disclosed are a preparation method for the crystal form, a pharmaceutical composition and use thereof. The crystal form of dezocine has good solubility, the preparation method has simple operations, good reproducibility, suitability for industrial production and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.